Patent
US 10,138,513METHOD AND DEVICE FOR AMPLIFYING AND DETECTING GENE USING GRAPHENE HEATER
Kwang Hyo CHUNG
US
Copyright © 2026 Matter42. All rights reserved.
Patent
Atlas literature
Patent
US 10,138,513Patent drawings and their descriptions. Click a drawing to enlarge it.
FIGS. 1 A and l B are cross-sectional views illustrating a structure of a gene amplifying/detecting device according to an embodiment of the present invention.
FIG. 2, a gene amplifying chip 500 is formed in a plate shape, graphene heaters 100a and 100 b are formed on both side surfaces of the gene amplifying chip …
FIG. 3, a light source 400 is located at one side of a gene amplifying chip 500, and a light detector 410 is located at the other side of the gene 15 …
FIGS. 4A to 4C are plan views illustrating various application examples of a gene amplifying chip 500 according to an embodiment of the present invention. 10 …
Claims define the patent's legal scope. Independent claims stand alone; dependent claims (nested) narrow them. Click a claim to expand its dependents.
A gene amplifying and detecting device, comprising: a gene amplifying chip including a chamber formed therein, the gene amplifying chip having a first sidewall and a second sidewall opposite to the first sidewall; a reaction solution in the chamber and including a fluorescent material; a light source adjacent to the first sidewall of the gene amplifying chip; a light detector located adjacent to the second sidewall of the gene amplifying chip; and a first graphene heater adjacent to the first sidewall of the gene amplifying chip so as to heat the reaction solution to cause a circulating flow of the reaction solution by convection, wherein the first graphene heater is positioned between the light source and the chamber to transmit light generated from the light source into the chamber. Previously presented
The device of claim 1, wherein the first graphene heater is in contact with the first sidewall of the gene amplifying chip. Previously presented
The device of claim 1, wherein the first graphene heater is formed in the gene amplifying chip to be in contact with the chamber. Previously presented
The device of claim 1, wherein the first graphene heater is formed of a single layer graphene or a multilayer graphene having a transmittance of 80 % or more. Previously presented
The device of claim 1, further comprising a second graphene heater adjacent to the second sidewall of the gene amplifying chip. Previously presented
The device of claim 1, wherein the second graphene heater is positioned between the chamber and the light detector, the transmitted light is adsorbed into the fluorescent material included in the reaction solution, the adsorbed light excites and is emitted from the fluorescent material, and the emitted light is detected by the light detector through the second graphene heater. Previously presented
The device of claim 1, wherein the fluorescent material emits light in proportion to a number of genes included in the reaction solution, and an amount of amplified gene products is measured through an intensity of emitted light measured by the light detector. Previously presented
The device of claim 1, wherein the gene amplifying chip is formed of a transparent material. Original
The device of claim 1, wherein the reaction solution includes one of a first reaction solution for gene amplification and a second reaction solution for gene preprocessing for purification and enrichment of genes in a sample. Previously presented
The device of claim 1, further comprising a first light filter located between the light source and the gene amplifying chip and a second light filter located between the light detector and the gene amplifying chip. Previously presented
The device of claim 1, further comprising a temperature sensor formed in the gene amplifying chip and configured to sense a temperature of the reaction solution. Original
The device of claim 1, further comprising a protection layer formed on the graphene heater and including a chemical doping material, a metal material, a glass material, graphene oxide, or a nanostructure. Original
The gene amplifying and detecting device of claim 1, wherein: the first graphene heater has a first width and the chamber has a second width parallel to the first width, and the first width is greater than the second width. Previously presented
The gene amplifying and detecting device of claim 1, wherein the chamber is in a ring shape. Previously presented
Canceled
Canceled
Canceled
Canceled
Layer stacks claimed or described, ordered top of device to substrate.
gene amplifying and detecting device
Materials described outside the worked examples.
graphene heater
single layer graphene
Performance values and ranges asserted in the specification or claims.
| Property | Value | Material |
|---|---|---|
graphene heater transmittance (claimed minimum) | 80 | graphene heater |
Patent
Atlas literature
Patent
US 10,138,513Patent drawings and their descriptions. Click a drawing to enlarge it.
FIGS. 1 A and l B are cross-sectional views illustrating a structure of a gene amplifying/detecting device according to an embodiment of the present invention.
FIG. 2, a gene amplifying chip 500 is formed in a plate shape, graphene heaters 100a and 100 b are formed on both side surfaces of the gene amplifying chip …
FIG. 3, a light source 400 is located at one side of a gene amplifying chip 500, and a light detector 410 is located at the other side of the gene 15 …
FIGS. 4A to 4C are plan views illustrating various application examples of a gene amplifying chip 500 according to an embodiment of the present invention. 10 …
Claims define the patent's legal scope. Independent claims stand alone; dependent claims (nested) narrow them. Click a claim to expand its dependents.
A gene amplifying and detecting device, comprising: a gene amplifying chip including a chamber formed therein, the gene amplifying chip having a first sidewall and a second sidewall opposite to the first sidewall; a reaction solution in the chamber and including a fluorescent material; a light source adjacent to the first sidewall of the gene amplifying chip; a light detector located adjacent to the second sidewall of the gene amplifying chip; and a first graphene heater adjacent to the first sidewall of the gene amplifying chip so as to heat the reaction solution to cause a circulating flow of the reaction solution by convection, wherein the first graphene heater is positioned between the light source and the chamber to transmit light generated from the light source into the chamber. Previously presented
The device of claim 1, wherein the first graphene heater is in contact with the first sidewall of the gene amplifying chip. Previously presented
The device of claim 1, wherein the first graphene heater is formed in the gene amplifying chip to be in contact with the chamber. Previously presented
The device of claim 1, wherein the first graphene heater is formed of a single layer graphene or a multilayer graphene having a transmittance of 80 % or more. Previously presented
The device of claim 1, further comprising a second graphene heater adjacent to the second sidewall of the gene amplifying chip. Previously presented
The device of claim 1, wherein the second graphene heater is positioned between the chamber and the light detector, the transmitted light is adsorbed into the fluorescent material included in the reaction solution, the adsorbed light excites and is emitted from the fluorescent material, and the emitted light is detected by the light detector through the second graphene heater. Previously presented
The device of claim 1, wherein the fluorescent material emits light in proportion to a number of genes included in the reaction solution, and an amount of amplified gene products is measured through an intensity of emitted light measured by the light detector. Previously presented
The device of claim 1, wherein the gene amplifying chip is formed of a transparent material. Original
The device of claim 1, wherein the reaction solution includes one of a first reaction solution for gene amplification and a second reaction solution for gene preprocessing for purification and enrichment of genes in a sample. Previously presented
The device of claim 1, further comprising a first light filter located between the light source and the gene amplifying chip and a second light filter located between the light detector and the gene amplifying chip. Previously presented
The device of claim 1, further comprising a temperature sensor formed in the gene amplifying chip and configured to sense a temperature of the reaction solution. Original
The device of claim 1, further comprising a protection layer formed on the graphene heater and including a chemical doping material, a metal material, a glass material, graphene oxide, or a nanostructure. Original
The gene amplifying and detecting device of claim 1, wherein: the first graphene heater has a first width and the chamber has a second width parallel to the first width, and the first width is greater than the second width. Previously presented
The gene amplifying and detecting device of claim 1, wherein the chamber is in a ring shape. Previously presented
Canceled
Canceled
Canceled
Canceled
Layer stacks claimed or described, ordered top of device to substrate.
gene amplifying and detecting device
Materials described outside the worked examples.
graphene heater
single layer graphene
Performance values and ranges asserted in the specification or claims.
| Property | Value | Material |
|---|---|---|
graphene heater transmittance (claimed minimum) | 80 | graphene heater |
Patent
Atlas literature
Patent
US 10,138,513Patent drawings and their descriptions. Click a drawing to enlarge it.
FIGS. 1 A and l B are cross-sectional views illustrating a structure of a gene amplifying/detecting device according to an embodiment of the present invention.
FIG. 2, a gene amplifying chip 500 is formed in a plate shape, graphene heaters 100a and 100 b are formed on both side surfaces of the gene amplifying chip …
FIG. 3, a light source 400 is located at one side of a gene amplifying chip 500, and a light detector 410 is located at the other side of the gene 15 …
FIGS. 4A to 4C are plan views illustrating various application examples of a gene amplifying chip 500 according to an embodiment of the present invention. 10 …
Claims define the patent's legal scope. Independent claims stand alone; dependent claims (nested) narrow them. Click a claim to expand its dependents.
A gene amplifying and detecting device, comprising: a gene amplifying chip including a chamber formed therein, the gene amplifying chip having a first sidewall and a second sidewall opposite to the first sidewall; a reaction solution in the chamber and including a fluorescent material; a light source adjacent to the first sidewall of the gene amplifying chip; a light detector located adjacent to the second sidewall of the gene amplifying chip; and a first graphene heater adjacent to the first sidewall of the gene amplifying chip so as to heat the reaction solution to cause a circulating flow of the reaction solution by convection, wherein the first graphene heater is positioned between the light source and the chamber to transmit light generated from the light source into the chamber. Previously presented
The device of claim 1, wherein the first graphene heater is in contact with the first sidewall of the gene amplifying chip. Previously presented
The device of claim 1, wherein the first graphene heater is formed in the gene amplifying chip to be in contact with the chamber. Previously presented
The device of claim 1, wherein the first graphene heater is formed of a single layer graphene or a multilayer graphene having a transmittance of 80 % or more. Previously presented
The device of claim 1, further comprising a second graphene heater adjacent to the second sidewall of the gene amplifying chip. Previously presented
The device of claim 1, wherein the second graphene heater is positioned between the chamber and the light detector, the transmitted light is adsorbed into the fluorescent material included in the reaction solution, the adsorbed light excites and is emitted from the fluorescent material, and the emitted light is detected by the light detector through the second graphene heater. Previously presented
The device of claim 1, wherein the fluorescent material emits light in proportion to a number of genes included in the reaction solution, and an amount of amplified gene products is measured through an intensity of emitted light measured by the light detector. Previously presented
The device of claim 1, wherein the gene amplifying chip is formed of a transparent material. Original
The device of claim 1, wherein the reaction solution includes one of a first reaction solution for gene amplification and a second reaction solution for gene preprocessing for purification and enrichment of genes in a sample. Previously presented
The device of claim 1, further comprising a first light filter located between the light source and the gene amplifying chip and a second light filter located between the light detector and the gene amplifying chip. Previously presented
The device of claim 1, further comprising a temperature sensor formed in the gene amplifying chip and configured to sense a temperature of the reaction solution. Original
The device of claim 1, further comprising a protection layer formed on the graphene heater and including a chemical doping material, a metal material, a glass material, graphene oxide, or a nanostructure. Original
The gene amplifying and detecting device of claim 1, wherein: the first graphene heater has a first width and the chamber has a second width parallel to the first width, and the first width is greater than the second width. Previously presented
The gene amplifying and detecting device of claim 1, wherein the chamber is in a ring shape. Previously presented
Canceled
Canceled
Canceled
Canceled
Layer stacks claimed or described, ordered top of device to substrate.
gene amplifying and detecting device
Materials described outside the worked examples.
graphene heater
single layer graphene
Performance values and ranges asserted in the specification or claims.
| Property | Value | Material |
|---|---|---|
graphene heater transmittance (claimed minimum) | 80 | graphene heater |
Patent
Atlas literature
Patent
US 10,138,513Patent drawings and their descriptions. Click a drawing to enlarge it.
FIGS. 1 A and l B are cross-sectional views illustrating a structure of a gene amplifying/detecting device according to an embodiment of the present invention.
FIG. 2, a gene amplifying chip 500 is formed in a plate shape, graphene heaters 100a and 100 b are formed on both side surfaces of the gene amplifying chip …
FIG. 3, a light source 400 is located at one side of a gene amplifying chip 500, and a light detector 410 is located at the other side of the gene 15 …
FIGS. 4A to 4C are plan views illustrating various application examples of a gene amplifying chip 500 according to an embodiment of the present invention. 10 …
Claims define the patent's legal scope. Independent claims stand alone; dependent claims (nested) narrow them. Click a claim to expand its dependents.
A gene amplifying and detecting device, comprising: a gene amplifying chip including a chamber formed therein, the gene amplifying chip having a first sidewall and a second sidewall opposite to the first sidewall; a reaction solution in the chamber and including a fluorescent material; a light source adjacent to the first sidewall of the gene amplifying chip; a light detector located adjacent to the second sidewall of the gene amplifying chip; and a first graphene heater adjacent to the first sidewall of the gene amplifying chip so as to heat the reaction solution to cause a circulating flow of the reaction solution by convection, wherein the first graphene heater is positioned between the light source and the chamber to transmit light generated from the light source into the chamber. Previously presented
The device of claim 1, wherein the first graphene heater is in contact with the first sidewall of the gene amplifying chip. Previously presented
The device of claim 1, wherein the first graphene heater is formed in the gene amplifying chip to be in contact with the chamber. Previously presented
The device of claim 1, wherein the first graphene heater is formed of a single layer graphene or a multilayer graphene having a transmittance of 80 % or more. Previously presented
The device of claim 1, further comprising a second graphene heater adjacent to the second sidewall of the gene amplifying chip. Previously presented
The device of claim 1, wherein the second graphene heater is positioned between the chamber and the light detector, the transmitted light is adsorbed into the fluorescent material included in the reaction solution, the adsorbed light excites and is emitted from the fluorescent material, and the emitted light is detected by the light detector through the second graphene heater. Previously presented
The device of claim 1, wherein the fluorescent material emits light in proportion to a number of genes included in the reaction solution, and an amount of amplified gene products is measured through an intensity of emitted light measured by the light detector. Previously presented
The device of claim 1, wherein the gene amplifying chip is formed of a transparent material. Original
The device of claim 1, wherein the reaction solution includes one of a first reaction solution for gene amplification and a second reaction solution for gene preprocessing for purification and enrichment of genes in a sample. Previously presented
The device of claim 1, further comprising a first light filter located between the light source and the gene amplifying chip and a second light filter located between the light detector and the gene amplifying chip. Previously presented
The device of claim 1, further comprising a temperature sensor formed in the gene amplifying chip and configured to sense a temperature of the reaction solution. Original
The device of claim 1, further comprising a protection layer formed on the graphene heater and including a chemical doping material, a metal material, a glass material, graphene oxide, or a nanostructure. Original
The gene amplifying and detecting device of claim 1, wherein: the first graphene heater has a first width and the chamber has a second width parallel to the first width, and the first width is greater than the second width. Previously presented
The gene amplifying and detecting device of claim 1, wherein the chamber is in a ring shape. Previously presented
Canceled
Canceled
Canceled
Canceled
Layer stacks claimed or described, ordered top of device to substrate.
gene amplifying and detecting device
Materials described outside the worked examples.
graphene heater
single layer graphene
Performance values and ranges asserted in the specification or claims.
| Property | Value | Material |
|---|---|---|
graphene heater transmittance (claimed minimum) | 80 | graphene heater |
multilayer graphene
reduced graphene oxide
fluorescent material
graphene oxide
multilayer graphene
reduced graphene oxide
fluorescent material
graphene oxide
multilayer graphene
reduced graphene oxide
fluorescent material
graphene oxide
multilayer graphene
reduced graphene oxide
fluorescent material
graphene oxide